Research Area	Population Genetics
Lab Website	Lab Website
Google Scholar	Google Scholar
ResearchMap	https://researchmap.jp/hinnan
E-mail	innan_hideki (at) soken.ac.jp

We explore how organisms evolve at the molecular level. The major focus is on the population process, where new mutations arise which are subsequently subject to selection and random genetic drift. We mainly use a theoretical approach to understand the evolutionary mechanisms behind inter- and intra-specific DNA variation under a wide range of evolutionary forces, such as adaptive selection, balancing selection, speciation, gene duplication. The accumulation of these studies promises to provide profound insights into the overarching principles governing molecular evolution.

Selected Publications, Books etc.

• 1.Fawcett, J. A., and H. Innan, 2013. The role of gene conversion in preservation of rearrangement hotspots in the human genome. Trends Genet. 29: 561-568.
• 2.Innan, H., and F. Kondrashov, 2010. The evolution of gene duplications: classifying and distinguishing between models. Nat. Rev. Genet. 11: 97-108.
• 3.Osada, N., and H. Innan, 2008. Duplication and gene conversion in the Drosophila melanogaster genome. PLoS Genet. 4: e1000305.
• 4.Gao, L. Z., and H. Innan, 2004. Very low gene duplication rate in the yeast genome. Science 306: 1367-1370.
• 5.Innan, H., 2003. A two-locus gene conversion model with selection and its application to the human RHCE and RHD genes. PNAS 100: 8793-8798.